Center For Uterine Fibroids

Brigham and Women's Hospital · 77 Avenue Louis Pasteur · 160, New Research Building · Boston, MA 02115
Tel: 800 722-5520 (ask operator for 525-4434)
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Publications

Note: More recent publications will be added soon.

General Interest Articles

Researchers Discover Gene Related to Fibroids (As published by Reuters Health, 2002.)

Ultrasound Surgery Shrinks Symptomatic Uterine Fibroids (As published by Reuters Health, 2001.)

Gene Dreams (As published in BWH 1997.)

Researchers Take Aim at Uterine Fibroids (As published in the Washington Post, April 6, 1999.)

 

Scientific Articles
  1. Analysis of androgen receptor DNA reveals the independent clonal origins of uterine leiomyomata and the secondary nature of cytogenetic aberrations in the development of leiomyomata. (PubMed abstract)
  2. Chromosome aberrations in uterine smooth muscle tumors: potential diagnostic relevance of cytogenetic instability. (PubMed abstract)
  3. Cytogenetic abnormalities in uterine myomas are associated with myoma size. (Full article; PubMed abstract)
  4. Disruption of the architectural factor HMGI-C: DNA binding AT hook motifs fused in lipomas to destinct transcritional regulatory domains. (Abstract and figures; PubMed abstract)
  5. Disseminated peritoneal leiomymomatosis: Clonality analysis by X chromosome inactivation and cytogenetics. (Abstract and figures; PubMed abstract)
  6. Expression of the fibroblast growth factor receptor in women with leiomyomas and abnormal uterine bleeding (Full article; PubMed abstract)
  7. Frequent loss of heterozygosity for chromosome 10 in uterine leiomyosarcoma in contrast to leiomyoma. (Full article (PDF format); PubMed abstract)
  8. Genetics and the development of fibroids (PubMed abstract)
  9. Genetics of uterine leiomyomata. (PubMed abstract)
  10. Glycoprotein hormones and their common alpha-subunit stimulate prolactin production by explant cultures of human leiomyomata and myometrium. (Pub Med abstract)
  11. HMGI(Y) expression in human uterine leiomyomata: Involvement of another HMG architectural factor in a benign neoplasm. (Abstract and figures; PubMed abstract)
  12. Identification of a YAC spanning the translocation breakpoints in uterine leiomyomata, pulmonary chondroid hamartoma, and lipoma. (PubMed abstract)
  13. Increased expression of stromelysin 3 mRNA in leiomyomas (uterine fibroids) compared with myometrium. (Pub Med abstract)
  14. Intravenous leiomyomatosis : molecular and cytogenetic analysis of a case. (PubMed abstract)
  15. Leiomyoma-related bleeding : a classic hypothesis updated for the molecular era (Full article; PubMed abstract)
  16. Leuprolide acetate-treated leiomyomas retain their relative overexpression of collagen type I and collagen type III messenger ribonucleic acid. (Abstract and figures; Pub Med abstract)
  17. New concepts in the treatment of uterine leiomyomas. (PubMed abstract)
  18. Pathology, cytogenetics,and molecular biology of uterine leiomyomas and other smooth muscle lesions (PubMed abstract)
  19. Pirfenidone: a novel pharmacological agent that inhibits leiomyoma cell proliferation and collagen production. (Full article; PubMed abstract)
  20. Predictors of subsequent surgery for uterine leiomyomata after abdominal myomectomy. (PubMed abstract)
  21. Production of prolactin by smooth muscle cells cultured from human uterine fibroid tumors. (PubMed abstract)
  22. Relative overexpression of collagen type I and collagen type III messenger ribonucleic acids by uterine leiomyomas during the proliferative phase of the menstrual cycle. (PubMed abstract)
  23. Relative over expression of the parathyroid hormone-related protein gene in human leiomyomas. (PubMed abstract)
  24. RU486 suppresses prolactin production in explant cultures of leiomyoma and myometrium. (Abstract and figures; PubMed abstract)
  25. The del(7q) subgroup in uterine leiomyomata: genetic and biologic characteristics. Further evidence for the secondary nature of cytogenetic abnormalities in the pathobiology of uterine leiomyomata. (Abstract and figures; PubMed abstract)
  26. Translocation breakpoints upstream of the HMGIC gene in uterine leiomyomata suggest dysregulation of this gene by a mechanism different from that in lipomas. (PubMed abstract)
  27. Translocations in 7q22 define a critical region in uterine leiomyomata. (Abstract and figures; PubMed abstract)
  28. Uterine Fibroids. (PubMed abstract)